What crisis is currently affecting executive departments according to Ari Melber?

According to Ari Melber, there's a significant crisis at the top of several important executive departments, most notably marked by the FDA chief's resignation. This high-level official stepped down with explicit warnings about potential dangers to public safety. This situation has direct implications for everyday Americans' lives, particularly regarding the safety of food and prescription medications that the FDA oversees. Melber emphasizes that what might seem like distant political turmoil actually impacts people's 'real life existence' through the regulatory protections these agencies provide.